Work Package 1 (WP1): Collection of Samples & GenomeWide Data
Objectives
1. Collection of blood samples from approximately 1,100 individuals from 21 geographic regions (to be added to an existing collection of samples from Greece and the Hellenic diaspora)
2. DNA extraction from whole blood and organization of samples in working plates
3. Genotyping for 2.5 million markers using a genomewide array
4. Genomewide imputation tests of representative samples
5. Compliance with national and international standards of ethics for research involving human subjects.
Deliverables
a. Collection of samples from populations in Greece and Hellenic diaspora
b. Genotypes on selected individuals for 2.5 million polymorphic markers
c. Genomewide imputation report of sequences for selected individuals